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Testosterone: What It Is, Function & Levels
High testosterone in women ups risk for cancer, diabetes, and metabolic disease
An individual can speak with their insurance provider to determine if testosterone testing is covered in their health plan. A 2022 analysis found that free testosterone may have links with prostate cancer, including early onset prostate cancer and aggressive prostate cancer. Testosterone is essential for health, but too much may increase the risk of health problems, such as an enlarged prostate gland. Androgen excess encourages fat to shift from subcutaneous areas (such as the hips and thighs) to visceral areas (inside the abdomen), resulting in a thicker waist and heavier upper body.
Although androgen excess can manifest in many ways, the most common and recognizable symptoms are hirsutism and acne. Acne vulgaris is a multifactorial skin condition of varying severity that affects as many as 90% of all adolescents 2. It is critical that the commonality of these conditions does not lead obstetrician–gynecologists and other health care providers to dismiss them as trivial. In patients with symptoms of androgen excess, the differential diagnosis should include physiologic hyperandrogenism of puberty, idiopathic hyperandrogenism, and PCOS. Other less common potential causes of hyperandrogenism include nonclassic congenital adrenal hyperplasia, androgen-secreting tumors, hypothyroidism, Cushing disease, and severe hyperprolactinemia.
In general, however, adult men may not notice symptoms of too much testosterone. Women with high testosterone develop many noticeable symptoms and signs such as unusual hair growth, obesity, hoarseness, and menstrual irregularities. On physical examination, body mass index, blood pressure, and signs of hyperandrogenism, such as acne and hirsutism, should be evaluated. It also is useful to assess for signs of insulin resistance, such as hypertension, obesity, centripetal fat distribution, skin tags, and acanthosis nigricans. Modified Ferriman–Gallwey Figure 2 scoring evaluates nine areas of the body; a score greater than 8 is indicative of hirsutism 3.
It blocks 11beta-hydroxysteroid dehydrogenase type 2, which can lead to licorice ingestion syndrome, marked with hypertension, hypokalemia, and metabolic acidosis. There are a number of ways people with PCOS can lower their testosterone levels. Polycystic ovary (or ovarian) syndrome (PCOS) is a common health problem caused by a hormonal imbalance. It causes egg follicles to not fully develop, resulting in multiple small cysts on and in the ovaries and reduced fertility. Oral contraceptives may not be ideal for people who are trying to get pregnant, so be sure to share your reproductive plans with your health care provider so they can determine an appropriate course of treatment.
The findings were consistent with an ovarian steroid-cell tumor (SCT) not otherwise specified (NOS), with cystic degeneration. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Getting help for my perimenopausal symptoms and mood swings has been a godsend. To check for PCOS, the doctor may perform an ultrasound of the ovaries and uterus.
It’s been found to be more common in some ethnic groups such as people of Hispanic, Mediterranean, Yugoslavian and Ashkenazi Jewish descent. It remains bound to a protein called, sex hormone-binding globulin (SHBG). The small amount of testosterone that’s unbound and therefore active, is called freely circulating testosterone (free T). Everyone produces and requires a certain amount of androgen hormones for reproductive development. The difference is just how much testosterone we have based on our sex-at-birth. There are a lot of misconceptions about testosterone being just a “male” hormone.
In some cases, women with PCOS-related hyperandrogenism no longer have PCOS after significant weight reduction. Most people, however, need continued therapy throughout their lifetime to minimize signs and symptoms of hyperandrogenism. If your provider suspects hyperandrogenism, they’ll likely order blood tests to measure certain hormone levels.
This is one reason it’s so important to get on a good treatment plan, which can help improve those physical symptoms and, as a result, improve mood and quality of life. As women approach menopause, testosterone (just like estrogen and progesterone) will start to dip. In fact, at around age 30, testosterone levels start gently declining at a rate of about 1% to 2% per year; by the time you hit menopause, levels are approximately half of what happens when a woman has too much testosterone they were at their peak. But for some women, testosterone can actually shoot up in the other direction.
Low testosterone levels effects and treatments in women are still being researched and treatment is usually recommended only if symptoms are significantly impacting health and quality of life. As it’s produced in the ovaries, the natural decrease in ovarian function with age means that some may experience low testosterone levels as they transition from the perimenopausal phase into menopause. Some women who are overweight may have high levels of testosterone which can be a factor in polycystic ovarian syndrome (PCOS), and reducing weight is a key factor in managing symptoms.